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KMID : 0383819910380010074
Tuberculosis and Respiratory Diseases
1991 Volume.38 No. 1 p.74 ~ p.82
A Report of Two Cases of Bronchial Carcinoid, Including One Case of Atypical Carcinoid
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Abstract
Bronchial carcinoid is one of the unusual tumors of the lung, accounting for 1 percent
of all lung tumors. Carcinoids, like small-cell carcinomas, are generally considered to be
derived from a neurosecretary type of cell of the respiratory epithelium, the Kulchtsky's
cell. So, they are no longer classified as bronchial adenoma, and are recently grouped
into the neuroendocrine group of tumors, the so-called APUD (Amine Precursor Uptake
Decarboxylase) group of tumors.
Although usually characterized by a slow growth pattern and a low incidence of
metastatic disease, bronchial carcinoids should no longer be considered as beings, and a
much higher malignant behavior has been described with a special destignation of
`atypical carcinoid'. Bronchial carcinoids are histologically confirmed by the azurophil
staining and the presence of the characteristic neurosecretary granule on electron
microscopy.
Recently we experienced two cases of bronchial carcinoid, the first case, being
peripheral-located and histologically proven as atypical carcinoid, and the second, being
central-located and hitologically typical. So we report these cases with a review of the
literature.
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